Hi folks,
I've been theming a lot of Drupal instances recently, and have found that the CSS and JS caches can be a real pain to clear every time you want to make an update. In my frustrations, I turned to Google, and found the following little gem.
To turn off CSS caching, use the following drush command:
drush vset preprocess_css 0 --yes
This can be done for JS as follows:
drush vset preprocess_js 0 --yes
The last thing you may want to do is clear the current CSS/JS cache. For that, the following command will suffice:
drush cc css+js
Useful stuff! Saves fannying about trekking through menus, as Drupal is wont to force.
SOURCE: OPC IT